منابع مشابه
Serum free thyroxine and free triiodothyronine concentrations in pregnancy.
Blood was taken from women in each trimester of pregnancy at routine antenatal visits. Further samples were collected from an age matched control group of euthyroid women taking no medication. Free triiodothyronine and free thyroxine concentrations were measured by direct radioimmunoassay (Amerlex Kit methods, Amersham International, Amersham, Buckinghamshire).2 These free hormone assays use th...
متن کاملMeasurement of "free" thyroxine in serum.
A dialysis method for determining “free” thyroxine in diluted serum is presented. The effect of a number of variables (pH, incubation time and temperature, buffer composition and concentration, protein concentration, and specimen dilution) was studied, and pertinent data are presented. Withinrun precision (95% confidence limits) was ±10.6%; between-run precision was ±14.2%. Specimens from 84 he...
متن کاملEuthyroid patient with elevated serum free thyroxine.
A 32-year-old female patient presented complaining of increased flushing, perspiration and heat intolerance of 3 months’ duration. Medical history included idiopathic thrombocytopenic purpura of 4 years’ duration, which had been treated by splenectomy after failed immunosuppression with prednisone and azathioprine and was currently in remission. On examination, she was found to be clinically eu...
متن کاملLevothyroxine therapy and serum free thyroxine and free triiodothyronine concentrations.
Although the normal thyroid gland secretes both levothyroxine (L-T4) and levotriiodothyronine (L-T3), normalization of serum TSH with L-T4-replacement therapy alone in hypothyroidism is generally believed to result in a normal serum L-T3 and to reflect a euthyroid state. However several recent studies suggest that this may not be the case. Accordingly, the relationship between serum free L-T4 a...
متن کاملDetermination of free thyroxine in serum by radioimmunoassay.
We describe a sensitive and specific radioimmunoassay for free thyroxine, directly determined in the diffusate obtained from equilibrium dialysis of serum. The intra- and interassay precisions were 7.5 +/- 0.27 and 9.1 +/- 0.58 ng/liter (mean +/- SD), respectively. The free thyroxine concentrations of normal persons and patients with thyroid disease were as follows: normal, 7.6 +/- 1.7; euthyro...
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ژورنال
عنوان ژورنال: BMJ
سال: 1979
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.6189.550-b